The Media Line has an interesting look on the increase of the number of Syrian refugees in the neighboring countries:
“The West wants to punish Al-Assad by imposing sanctions on his regime, but they are also punishing the people. Citizens are suffering as a result of the sanctions and uncertainty in the pound value,” says activist Islam Abdullah from the Syrian Media Center.
He says hundreds of Syrian families have chosen to flee to Jordan and other neighboring countries in search of food rather than for safety. In Jordan, they receive aid from non-government organizations and ordinary Jordanian citizens.
According to this article ("Exclusive: Syria buys grain via Lebanon to beat sanctions"): Growing numbers of Syrians are struggling to obtain food, with prices of staples more than doubling.. This may have been caused by the fact that the exchange rate of the Syrian currency has fallen to half.
There is also a shortage of LPG gas that is mainly used for cooking and hearing.
Here is an article in Spiegel and here the German original about war profiteers in Syria. Just like in any other sanctioned country those connected to the regime profit from the sanctions while the common man suffers.